The PeriScan PIM 3 System is a blood perfusion imager based on the laser Doppler technology. It is a proven technique with a documented linearity between the measured blood perfusion and the true blood perfusion in the tissue being imaged. By scanning across the tissue with a stepwise moving laser beam, color-coded images of the microcirculatory blood perfusion are created. The PeriScan PIM 3 can visualize spatial blood perfusion over time in large measurement areas up to 50 x 50 cm, each image consisting of up to 255×255 discrete measurement points.
The PeriScan PIM 3 is easy to get started and to operate. It is flexible to adjust and position at any measurement distance and angle. A color camera for documentation, and automated working distance calculation increases the simplicity.
Pre-defined Regions Of Interest (ROIs) allows for on-line analysis while recording, presenting data, graphs and images.
Using a patented stepwise movement of the laser beam across the tissue, background noise is kept to a minimum, improving the quality of measurements in minimally perfused areas.
The PeriScan PIM 3 system uses a low-power, 658 nm red laser for blood perfusion measurements. The laser beam is reflected down to the tissue via a moving mirror that moves the beam from site to site. A photo detector collects the back scattered light in each measurement point and from this informationthe blood perfusion is calculated.
Although the scanning motion of the laser beam appears continuous to the eye, each measurement is in reality made up of a number of discrete measurement points. In each point, the laser beam stops for some milliseconds to sample the perfusion in the tissue before moving on to the next site. The maximum number of measurement points is 255×255, which means that more than 65 000 separate tissue sites can be scanned in one image.
A color camera is used for documentation. The capture rate can be set at different speeds during a recording, up to 1 frame per perfusion image. The color photos provide an extra help when analyzing the perfusion data, assuring that the object has not moved during the recording and for understanding the obtained blood perfusion images.
The drawing of the imager head shows the laser, the color camera, the photo detector, and the moving mirror.
Blood perfusion is presented both as color-coded images and in graphical form, enhancing the possibilities for understanding and analyzing the microcirculatory data. Specific regions of interest (ROIs) can be defined before, during or after a completed recording. In addition, ROIs may be implemented during sections of a run. Time periods Of Interest (TOIs) allow for evaluation of blood perfusion during specific time periods. Event markers with comments may be added at any time.
Automatically calculated values include mean, percentage change, number of measurement points, standard deviation and more. Selected data is conveniently exported as .pdf reports or in .xml format for further processing.
The PeriScan PIM 3 System has many different microcirculatory applications in humans and animals. Common uses are burn wound assessment, non-healing wounds, flap surgery and development of skin care products. The imager can be mounted on a cart with a flexible arm that makes it easy to position and reach a patient lying on a bed. In animal research, the technique is commonly used for angiogenesis and stroke model research, or for imaging of organ blood perfusion during open surgery.
Manufactured by Perimed AB, Sweden